Vinculin Isoform Vcl

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-25   MET-26  10.2 2.8 -20.8 -11.2 15.3 40.2 52.7
 MET-26   HIS-27  8.3 0.7 166.6 60.1 136.4 87.3 83.6
 HIS-27   GLU-28  8.7 3.1 -146.3 37.1 54.4 62.2 -421.6
 ALA-36   ILE-37  5.1 5.8 -19.8 50.3 136.2 138.0 45.8
 ILE-37   PRO-38  5.1 5.5 -4.3 -8.9 81.6 85.3 -2.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-124   THR-125  2.0 2.1 4.1 -8.1 146.4 143.3 2.3
 THR-125   PHE-126  1.1 1.9 2.7 5.4 120.8 121.4 -12.8
 PHE-126   ASP-127  3.4 5.1 -17.8 7.1 68.1 58.9 21.7
 ASP-127   GLU-128  4.2 5.1 -2.6 1.6 30.5 36.4 5.2
 GLU-128   ALA-129  2.5 2.6 0.3 -6.2 141.4 143.1 7.6
 ALA-129   GLU-130  2.6 3.5 7.0 -3.1 109.7 111.5 -2.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees