Importin Alpha Subunit

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-243   ARG-244  3.5 3.5 1.7 3.0 57.0 57.5 65.1
 ARG-244   GLY-245  2.0 1.9 5.4 -9.6 11.2 9.7 -55.9
 GLY-245   LYS-246  2.4 2.4 5.4 -19.8 58.2 57.6 -121.7
 LYS-246   LYS-247  1.5 1.4 5.3 84.7 22.3 12.9 1144.0
 LYS-247   PRO-248  1.2 1.9 154.6 0.8 84.1 83.6 -1452.5
 LYS-247   PRO-248  1.2 1.9 154.6 0.8 84.1 83.6 -1452.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-247   PRO-248  1.2 1.9 154.6 0.8 84.1 83.6 -1452.5
 LYS-247   PRO-248  1.2 1.9 154.6 0.8 84.1 83.6 -1452.5
 PRO-248   GLN-249  2.8 3.0 -48.2 8.2 25.3 33.1 531.5
 GLN-249   PRO-250  3.2 3.3 -14.8 7.9 74.0 74.6 -17.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-253   VAL-254  13.7 13.9 15.5 -5.8 35.9 45.0 140.3
 VAL-254   VAL-255  12.8 12.7 1.1 -11.1 43.6 41.8 -75.7
 VAL-255   SER-256  9.5 9.5 4.8 0.5 64.0 63.0 21.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-259   PRO-260  10.9 10.7 -2.7 1.0 23.7 24.4 16.6
 PRO-260   THR-261  13.2 13.1 -9.1 8.4 46.5 44.0 7.6
 THR-261   LEU-262  10.6 10.6 -12.4 11.2 85.0 81.6 22.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-268   MET-269  4.6 4.5 -14.8 31.7 109.2 117.1 77.9
 MET-269   ASP-270  4.1 3.6 -19.9 2.7 87.7 75.4 -15.6
 ASP-270   THR-271  1.8 1.5 -5.5 6.1 35.1 37.0 -50.2
 THR-271   GLU-272  4.9 4.7 -3.8 -2.0 37.1 31.7 80.9
 GLU-272   THR-273  4.7 4.8 -2.5 6.7 59.8 59.2 -40.0
 THR-273   LEU-274  1.2 1.4 0.5 -2.2 122.4 118.8 6.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees