Isocitrate Dehydrogenase [Nadp] Cytoplasmic

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-117   PRO-118  2.9 2.4 -1.7 -20.8 113.3 99.6 -6.5
 PRO-118   ARG-119  3.6 3.3 9.9 19.0 14.5 39.8 80.3
 ARG-119   LEU-120  5.3 5.0 3.7 -32.9 91.1 108.9 -2.7
 LEU-120   VAL-121  7.9 7.9 5.9 27.4 104.4 72.2 4.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-132   HIS-133  6.1 4.7 -17.2 12.7 21.9 19.6 16.2
 HIS-133   ALA-134  6.9 5.4 -8.4 67.7 92.3 91.5 16.9
 ALA-134   TYR-135  8.3 6.1 -139.7 -45.5 40.7 42.1 408.7
 TYR-135   GLY-136  9.8 8.2 -13.8 140.0 116.7 84.3 -34.6
 GLY-136   ASP-137  10.5 11.6 27.3 127.0 77.1 45.3 -276.8
 ASP-137   GLN-138  14.0 14.3 -128.5 20.8 33.7 111.4 173.6
 GLN-138   TYR-139  15.0 16.5 -16.1 -4.1 69.9 91.2 91.0
 TYR-139   ARG-140  14.9 14.8 -124.5 -39.6 107.5 31.0 -438.3
 ARG-140   ALA-141  18.5 15.6 -84.0 -35.5 90.0 65.6 59.0
 ALA-141   THR-142  19.9 18.8 30.7 -17.9 131.4 105.8 -9.9
 THR-142   ASP-143  22.2 22.3 39.2 -0.6 65.3 64.9 47.2
 ASP-143   PHE-144  25.0 25.1 12.1 -24.9 94.7 91.0 0.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-268   CYS-269  8.0 8.1 -16.2 26.4 91.0 94.6 -21.7
 CYS-269   LYS-270  9.9 8.7 4.6 36.8 121.8 138.2 -81.8
 LYS-270   ASN-271  11.5 10.0 33.8 63.7 59.2 62.8 247.9
 ASN-271   TYR-272  13.9 9.7 144.0 -12.5 127.6 33.2 -110.9
 TYR-272   ASP-273  17.4 12.6 8.9 11.0 114.6 35.7 63.4
 ASP-273   GLY-274  17.2 11.9 -26.4 -139.2 63.8 113.8 -39.5
 GLY-274   ASP-275  13.6 8.1 148.7 73.9 52.4 57.0 352.6
 ASP-275   VAL-276  11.9 9.8 141.5 57.3 123.4 22.8 -113.7
 VAL-276   GLN-277  11.9 11.8 175.5 -12.7 54.9 52.1 -486.7
 GLN-277   SER-278  10.0 9.8 -162.1 69.2 121.3 111.3 -41.5
 SER-278   ASP-279  11.9 6.3 168.6 1.9 61.6 31.9 454.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees