Receptor Tyrosine-Protein Kinase Erbb-4

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-304   CYS-305  5.6 5.7 -9.1 -17.7 56.5 60.4 89.7
 CYS-305   PRO-306  3.7 3.8 -5.1 -1.3 56.2 55.1 19.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-507   ILE-508  11.8 11.8 -2.0 2.5 30.4 24.5 9.8
 ILE-508   GLU-509  10.8 11.0 5.2 -2.8 141.5 135.4 -18.1
 GLU-509   SER-510  11.1 11.1 0.0 -0.7 104.7 101.5 -3.9
 SER-510   CYS-511  7.6 7.5 -3.4 9.1 112.0 107.6 28.6
 CYS-511   ASN-512  4.0 3.9 5.5 -6.2 136.1 137.8 -10.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-520   PHE-521  2.2 2.2 7.0 -6.0 66.9 72.6 -5.7
 PHE-521   GLU-522  4.8 3.9 -10.7 4.5 53.2 53.9 8.4
 GLU-522   ASN-523  6.5 5.5 0.0 -4.2 57.0 56.7 16.8
 ASN-523   ASP-524  8.7 7.6 -0.7 11.3 74.1 69.4 -21.9
 ASP-524   SER-525  11.4 10.3 -10.2 -2.1 79.4 87.4 23.4
 SER-525   ILE-526  9.9 9.1 13.3 -12.1 118.5 117.4 -19.0
 ILE-526   CYS-527  6.7 5.8 -3.9 5.3 124.7 121.5 -3.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees