Heparin Cofactor II

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-425   VAL-426  16.0 15.5 -7.6 13.6 79.3 79.9 1.0
 VAL-426   ASN-427  12.9 12.2 5.6 4.6 167.1 169.6 -22.3
 ASN-427   GLU-428  13.5 12.6 6.7 8.7 94.7 97.4 0.0
 GLU-428   GLU-429  13.4 12.2 -19.5 -28.0 114.2 123.7 -42.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-447   VAL-448  11.3 14.3 167.5 -68.4 149.9 95.5 -125.2
 VAL-448   ARG-449  10.5 11.1 59.5 -9.2 95.4 76.7 0.9
 ARG-449   PHE-450  6.8 7.4 -4.5 -30.3 43.8 57.7 40.0
 PHE-450   THR-451  4.4 5.0 15.6 -1.8 64.8 71.3 1.6
 THR-451   VAL-452  2.2 3.2 10.3 7.7 124.2 129.9 -20.6
 VAL-452   ASP-453  2.8 3.8 11.4 5.0 51.0 54.2 21.7
 ASP-453   ARG-454  5.7 7.0 -2.5 -10.4 72.7 64.6 9.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees