Proto-Oncogene Tyrosine-Protein Kinase Abl1
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-376
VAL-377
12.2
12.0
2.2
0.8
24.1
21.9
-2.0
VAL-377
LYS-378
11.4
11.2
10.2
-12.7
74.3
73.5
2.9
LYS-378
VAL-379
8.2
8.0
2.2
-7.8
9.3
15.0
2.2
VAL-379
ALA-380
7.6
7.3
3.4
63.9
87.1
84.1
4.7
ALA-380
ASP-381
4.2
4.2
-61.9
49.9
175.7
121.9
-11.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLY-398
ALA-399
3.8
2.2
7.7
23.3
18.0
24.5
24.9
ALA-399
LYS-400
2.5
2.5
-15.8
22.3
94.0
94.6
4.5
LYS-400
PHE-401
5.6
6.0
28.1
-14.4
59.8
34.1
10.5
PHE-401
PRO-402
7.2
7.6
5.2
12.7
71.3
73.3
5.6
PRO-402
ILE-403
10.5
10.7
-3.4
15.2
64.5
71.3
-3.4
ILE-403
LYS-404
12.6
13.0
-16.0
21.7
120.6
122.9
1.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees