Hiv-1 Reverse Transcriptase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ILE-326   ALA-327  5.6 4.9 -6.3 6.6 76.7 74.3 -4.4  ALA-327   GLU-328  5.8 5.2 -5.2 3.0 143.0 136.8 -37.3  GLU-328   ILE-329  9.0 8.6 -33.8 39.6 84.9 87.6 38.3  ILE-329   GLN-330  11.1 10.6 -5.9 16.8 63.0 73.4 -37.1  ILE-329   GLN-330  11.1 10.6 -5.9 16.8 63.0 73.4 -37.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ILE-329   GLN-330  11.1 10.6 -5.9 16.8 63.0 73.4 -37.1  ILE-329   GLN-330  11.1 10.6 -5.9 16.8 63.0 73.4 -37.1  GLN-330   LYS-331  14.8 14.4 -5.7 0.6 88.3 74.1 35.1  LYS-331   GLN-332  17.4 16.9 7.8 -5.9 61.8 57.4 -2.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-351   GLY-352  10.3 10.0 -8.9 5.9 97.4 86.5 -21.1  GLY-352   LYS-353  12.1 11.9 23.1 -28.8 37.8 40.4 -16.6  LYS-353   TYR-354  14.9 14.6 -34.8 35.6 124.8 106.6 6.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  VAL-365   LYS-366  13.2 13.6 -10.2 26.0 121.4 132.3 97.5  LYS-366   GLN-367  14.3 15.0 -13.3 13.3 172.1 163.5 11.3  GLN-367   LEU-368  15.2 15.6 -12.7 6.4 115.4 105.4 -17.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLU-370   ALA-371  12.6 12.9 3.4 6.2 149.3 139.5 -54.3  ALA-371   VAL-372  11.2 11.4 -5.0 -3.2 82.8 80.0 5.4  VAL-372   GLN-373  7.6 7.8 -12.3 13.0 69.2 66.7 3.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-377   GLU-378  8.9 8.9 -5.9 1.9 158.7 154.8 -30.8  GLU-378   SER-379  7.5 7.6 25.6 -32.2 76.0 73.1 37.4  SER-379   ILE-380  4.1 4.2 -5.5 18.4 101.9 101.1 80.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-388   PHE-389  3.8 2.6 12.4 -9.3 84.2 84.4 28.6  PHE-389   LYS-390  4.3 3.8 21.5 -22.7 55.8 56.9 40.3  LYS-390   LEU-391  7.9 7.4 -18.7 11.7 104.8 101.1 28.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees