Proto-Oncogene Tyrosine-Protein Kinase Src

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-185   LEU-186  2.2 2.3 1.0 -5.2 86.4 88.0 17.2
 LEU-186   VAL-187  2.3 2.2 -3.6 -3.0 120.1 118.4 -21.0
 VAL-187   ARG-188  4.5 4.5 0.6 -15.0 118.5 117.2 39.2
 ARG-188   GLU-189  7.9 7.8 11.5 33.0 59.1 69.2 131.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-212   LYS-213  7.0 7.0 10.3 -19.1 129.3 123.4 49.8
 LYS-213   HIS-214  8.6 8.5 11.0 -2.6 116.7 119.3 -22.3
 HIS-214   TYR-215  8.3 8.3 6.8 -8.2 147.2 147.3 5.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees