Epidermal Growth Factor Receptor
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LYS-721
GLU-722
7.0
6.8
-10.3
-1.0
72.3
73.9
-0.4
GLU-722
LEU-723
8.0
8.3
-29.0
-6.6
91.5
86.6
49.1
LYS-730
ALA-731
19.5
20.9
37.4
-3.0
118.4
36.8
128.0
ALA-731
ASN-732
19.8
19.2
-99.6
-38.4
102.7
96.2
-100.2
ASN-732
LYS-733
17.0
16.3
14.2
4.8
22.1
8.9
56.2
LYS-733
GLU-734
17.6
17.0
10.6
0.9
59.5
83.3
18.5
GLU-734
ILE-735
17.0
15.8
-20.7
11.0
73.4
80.8
-14.0
ILE-735
LEU-736
14.1
12.4
1.7
-10.0
67.9
46.1
-9.9
LEU-736
ASP-737
12.4
11.7
-2.4
-0.8
165.2
152.9
-19.9
ASP-737
GLU-738
12.9
12.3
12.1
-1.7
84.0
91.6
27.7
GLU-738
ALA-739
11.8
10.6
-16.9
11.5
73.0
95.2
2.1
ALA-739
TYR-740
8.6
7.5
-0.2
6.9
138.1
161.6
45.2
TYR-740
VAL-741
7.6
7.8
-15.0
-6.9
129.6
118.9
-55.5
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-750
CYS-751
10.6
10.4
3.6
-5.5
56.8
52.9
14.6
CYS-751
ARG-752
8.4
8.3
1.3
-8.2
103.9
103.5
-0.1
ARG-752
LEU-753
4.6
4.5
4.7
21.6
33.8
35.8
69.9
LEU-753
LEU-754
2.8
1.9
13.7
3.2
92.8
80.9
1.8
LEU-754
GLY-755
0.9
1.9
-1.4
-27.7
109.4
88.9
-51.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-765
THR-766
1.6
1.4
-16.0
11.8
146.8
140.2
-29.5
THR-766
GLN-767
4.0
3.6
-15.4
-13.3
71.2
69.7
60.6
GLN-767
LEU-768
6.9
6.1
-3.3
-33.3
53.4
67.6
88.8
LEU-768
MET-769
9.5
9.3
13.7
16.8
63.6
80.7
57.6
MET-769
PRO-770
12.9
12.6
37.0
-5.6
135.9
147.2
-84.5
PRO-770
PHE-771
15.7
14.8
1.3
3.2
106.7
109.0
-14.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees