Guanylate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-225   PRO-226  15.0 14.9 17.0 -5.9 68.5 67.6 58.7
 PRO-226   ASP-227  14.2 14.0 -2.1 -6.2 115.5 110.9 70.3
 ASP-227   SER-228  11.2 10.7 1.7 -6.9 127.8 128.1 101.5
 SER-228   PHE-229  10.0 9.4 19.6 10.7 123.7 136.5 -224.9
 PHE-229   GLY-230  8.4 8.6 -7.4 1.5 108.0 106.9 -49.5
 GLY-230   PHE-231  7.8 7.6 -31.4 30.1 46.7 38.9 93.6
 PHE-231   SER-232  8.1 8.6 3.6 -14.8 65.8 67.2 -72.7
 SER-232   VAL-233  7.6 7.8 -23.4 29.8 109.9 116.6 104.6
 VAL-233   SER-234  10.6 10.4 -3.9 12.4 55.4 58.2 17.3
 SER-234   SER-235  13.3 13.3 -4.5 7.4 119.0 117.4 65.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-292   LYS-293  4.3 4.2 27.7 -18.0 48.0 53.8 155.1
 LYS-293   THR-294  5.0 5.0 0.3 -4.4 20.2 16.8 -100.0
 THR-294   CYS-295  4.9 5.1 -26.5 25.7 111.9 110.7 17.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees