Hiv-1 Reverse Transcriptase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-425   TRP-426  5.9 6.6 -17.5 6.3 67.3 67.3 57.8
 TRP-426   TYR-427  5.2 5.3 12.3 -27.6 171.6 172.2 98.0
 TYR-427   GLN-428  4.2 4.4 0.0 -7.4 112.0 109.5 16.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-509   PRO-510  3.7 3.9 -11.5 -3.6 20.2 17.6 118.2
 PRO-510   ASP-511  3.8 3.6 7.0 9.8 97.1 91.8 -55.0
 ASP-511   GLN-512  1.9 1.6 -2.5 -9.8 45.9 56.5 48.1
 GLN-512   SER-513  4.7 4.7 3.7 -5.4 81.5 96.6 -24.9
 SER-513   GLU-514  8.2 8.1 -1.3 9.5 51.0 63.0 -61.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees