Importin-Alpha2 Subunit

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-253   PRO-254  8.0 8.2 -0.4 0.0 53.6 49.8 -1.7
 PRO-254   THR-255  11.4 11.4 -2.6 -0.6 15.8 17.4 25.8
 THR-255   LEU-256  11.0 11.0 -9.9 6.5 65.8 68.7 27.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-257   ARG-258  9.2 8.5 12.4 -6.2 27.1 28.3 61.8
 ARG-258   LEU-259  11.3 10.6 -0.2 -2.1 138.8 135.9 -21.9
 LEU-259   LEU-260  8.2 7.5 -4.4 1.4 106.9 98.6 -1.3
 LEU-260   HIS-261  7.3 6.2 -6.2 -12.7 130.9 125.7 -136.1
 HIS-261   HIS-262  10.4 9.4 17.5 -12.2 24.7 25.1 55.7
 HIS-262   ASN-263  8.9 8.5 -8.3 21.7 129.4 135.3 122.6
 ASN-263   ASP-264  7.7 7.7 -12.4 10.3 110.1 112.6 22.8
 ASP-264   PRO-265  4.5 4.6 6.4 -0.4 123.1 115.2 -25.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-270   SER-271  2.4 2.7 10.7 3.2 36.5 41.1 119.1
 SER-271   CYS-272  1.9 1.7 -4.0 -0.3 121.2 125.0 -22.5
 CYS-272   TRP-273  2.4 2.3 8.5 -9.4 58.8 57.3 -30.0
 TRP-273   ALA-274  3.3 3.4 4.5 -3.7 33.0 33.7 14.5
 ALA-274   ILE-275  2.0 2.2 -2.1 1.4 136.4 133.6 -6.0
 ILE-275   SER-276  1.4 1.4 -0.8 -1.0 112.9 112.6 -2.0
 ILE-275   SER-276  1.4 1.4 -0.8 -1.0 112.9 112.6 -2.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-275   SER-276  1.4 1.4 -0.8 -1.0 112.9 112.6 -2.0
 ILE-275   SER-276  1.4 1.4 -0.8 -1.0 112.9 112.6 -2.0
 SER-276   TYR-277  4.3 4.3 4.6 -1.5 45.3 44.3 32.2
 TYR-277   LEU-278  4.4 4.3 -8.1 8.0 147.1 146.0 -2.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-280   GLY-281  6.4 6.3 8.5 0.7 155.0 156.9 -87.5
 GLY-281   PRO-282  6.0 5.8 0.2 -14.6 132.0 130.5 108.3
 PRO-282   ASN-283  5.0 5.2 7.6 8.0 73.0 72.3 29.3
 ASN-283   GLU-284  6.3 6.5 -15.1 9.4 86.1 93.8 -10.2
 GLU-284   ARG-285  3.8 4.2 2.7 1.5 29.8 27.3 51.7
 ARG-285   ILE-286  2.0 2.2 -12.0 4.7 132.7 134.5 -71.5
 ILE-286   GLU-287  5.2 5.4 5.6 -7.7 97.1 93.5 -7.5
 GLU-287   MET-288  7.4 7.5 -1.7 -0.4 117.2 116.2 -74.0
 MET-288   VAL-289  6.7 6.8 27.5 -28.9 11.0 4.4 9.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees