Lysine-Specific Histone Demethylase 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-416   GLN-417  3.4 3.1 2.3 0.0 62.9 65.6 32.7
 GLN-417   LEU-418  4.2 4.1 -5.7 -0.5 48.1 48.3 36.1
 LEU-418   GLN-419  6.3 6.1 10.8 -13.9 124.9 124.1 29.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-514   PRO-515  18.9 19.4 -21.8 0.6 44.5 55.2 116.5
 PRO-515   PRO-516  17.0 17.7 -8.5 14.7 103.5 85.6 -40.1
 PRO-516   SER-517  13.3 13.9 -10.5 -10.8 50.2 36.3 60.3
 SER-517   ASP-518  11.0 12.0 0.7 4.0 169.3 151.1 -9.4
 ASP-518   VAL-519  11.6 11.9 7.5 -1.3 121.8 106.3 -2.9
 VAL-519   TYR-520  8.2 8.4 -5.5 -10.5 132.6 139.8 -113.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees