DNA Polymerase Iota

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-303   GLU-304  3.6 4.2 24.6 -57.7 18.8 33.5 -193.2
 GLU-304   GLU-305  2.9 3.2 -77.0 73.8 104.5 111.8 -9.0
 GLU-305   ASP-306  0.6 0.1 28.2 -15.0 36.6 46.8 115.4
 ASP-306   SER-307  3.2 2.7 27.7 21.5 72.5 53.7 197.2
 SER-307   PHE-308  4.8 4.3 91.2 -156.3 53.8 99.3 -173.3
 PHE-308   LYS-309  7.7 8.0 -44.8 -84.5 84.2 45.0 226.6
 LYS-309   LYS-310  10.3 9.2 -121.0 166.1 104.2 104.4 227.7
 LYS-310   CYS-311  13.7 8.7 -29.8 -34.1 76.0 156.2 -218.7
 CYS-311   SER-312  13.1 9.5 -29.9 -71.1 25.3 88.2 347.0
 SER-312   SER-313  13.7 11.7 34.9 -91.7 100.9 133.1 -1279.9
 SER-313   GLU-314  17.5 12.7 -120.2 85.0 29.0 83.2 -49.1
 GLU-314   VAL-315  17.5 15.9 -4.5 -108.3 53.1 11.3 648.6
 VAL-315   GLU-316  18.0 15.7 64.8 5.0 58.6 114.2 128.4
 GLU-316   ALA-317  18.0 14.2 172.8 -27.2 89.0 164.0 -488.0
 ALA-317   LYS-318  14.2 13.5 -158.2 98.3 20.2 77.4 347.2
 LYS-318   ASN-319  13.2 14.7 4.3 -55.0 75.9 56.5 -120.1
 ASN-319   LYS-320  14.0 12.4 7.5 -14.3 87.4 103.1 54.3
 LYS-320   ILE-321  10.4 9.3 58.1 -74.7 142.0 151.3 88.1
 ILE-321   GLU-322  9.3 9.4 0.0 -16.9 75.0 97.9 22.8
 GLU-322   GLU-323  11.5 11.5 13.7 -33.0 56.1 43.5 -85.5
 GLU-323   LEU-324  10.3 9.3 -3.0 -6.3 69.9 68.5 30.1
 LEU-324   LEU-325  6.9 5.8 14.0 -50.5 141.0 131.5 182.0
 LEU-325   ALA-326  8.7 7.7 77.8 -14.3 77.3 73.3 44.6
 ALA-326   SER-327  11.7 10.6 -43.5 -6.0 95.1 72.2 60.5
 SER-327   LEU-328  10.5 11.9 38.8 -7.7 145.6 137.7 -181.8
 LEU-328   LEU-329  8.4 9.2 34.6 -52.0 135.1 151.1 89.8
 LEU-329   ASN-330  11.2 11.7 -25.5 7.5 96.3 93.7 1.2
 ASN-330   ARG-331  13.7 15.3 29.7 -49.1 96.2 76.4 -33.4
 ARG-331   VAL-332  12.2 14.5 95.7 -68.4 160.6 127.9 -70.3
 VAL-332   CYS-333  10.9 13.2 30.5 -45.6 121.8 134.5 3.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-339   HIS-340  7.1 7.8 17.7 -34.5 136.6 139.5 58.4
 HIS-340   THR-341  4.7 5.0 20.1 -29.0 75.5 78.7 -3.0
 THR-341   VAL-342  1.5 1.7 -9.0 11.0 156.8 165.2 26.1
 VAL-342   ARG-343  2.0 1.4 0.5 -12.0 75.3 79.3 -34.8
 ARG-343   LEU-344  2.9 2.8 -19.3 15.7 150.8 161.7 -27.3
 LEU-344   ILE-345  5.5 5.0 -23.2 42.8 115.2 106.9 -1.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-358   SER-359  11.7 12.1 -58.6 57.4 111.3 103.2 23.8
 SER-359   ARG-360  9.0 8.7 41.2 -42.5 20.2 41.0 -4.3
 ARG-360   GLN-361  8.5 7.6 -13.4 -9.2 108.5 111.2 -88.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-388   LYS-389  13.1 12.9 93.8 -96.1 121.8 139.9 22.4
 LYS-389   LEU-390  13.7 13.5 4.2 -23.6 82.9 90.0 16.3
 LEU-390   PHE-391  10.7 11.1 32.8 -35.8 32.6 27.3 4.3
 PHE-391   ARG-392  12.1 12.5 -12.3 6.6 82.2 88.7 0.6
 ARG-392   ASN-393  15.6 16.1 52.2 -69.3 114.4 126.4 74.4
 ASN-393   MET-394  15.2 15.9 19.1 6.6 41.2 61.6 74.4
 THR-404   LEU-405  11.2 10.8 139.2 -10.3 104.9 162.6 -397.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-407   VAL-408  3.1 3.3 -42.8 12.1 163.0 161.1 -196.8
 VAL-408   CYS-409  2.3 1.5 14.2 -4.5 77.5 73.4 -26.7
 CYS-409   PHE-410  1.2 1.6 35.1 -33.7 24.8 39.2 38.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees