Importin Alpha Subunit

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-259   PRO-260  2.6 1.8 -1.2 -0.9 79.1 76.9 2.5
 PRO-260   THR-261  6.3 5.5 -6.7 9.4 54.1 55.6 -2.3
 THR-261   LEU-262  7.6 6.9 -7.5 1.4 22.1 19.8 41.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-265   ILE-266  8.9 8.3 2.5 1.2 26.4 23.8 17.1
 ILE-266   TYR-267  6.8 6.1 2.7 -8.3 61.2 57.0 12.6
 TYR-267   SER-268  10.2 9.5 -1.8 6.2 112.8 102.9 -8.5
 SER-268   MET-269  11.6 11.2 -11.0 26.0 170.8 172.4 127.6
 MET-269   ASP-270  12.2 12.8 -19.0 4.9 109.0 103.6 -77.0
 ASP-270   THR-271  13.1 13.4 -11.1 1.9 98.0 101.4 -20.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-282   TYR-283  5.5 6.1 2.3 2.3 46.3 46.2 29.4
 TYR-283   LEU-284  7.9 8.3 5.4 -6.0 37.9 39.2 -9.8
 LEU-284   SER-285  5.7 6.2 -1.8 2.1 78.8 75.4 -0.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees