DNA Mismatch Repair Protein Muts

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-1420   TYR-1421  6.7 5.7 -2.0 8.3 125.7 130.0 35.3
 TYR-1421   PHE-1422  3.8 3.1 3.2 1.3 34.2 40.6 37.6
 PHE-1422   LEU-1423  5.9 5.5 -11.4 5.3 80.9 76.6 -11.4
 LEU-1423   GLU-1424  8.9 8.5 1.5 -0.8 90.4 94.5 4.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-1482   GLU-1483  4.5 3.9 8.8 -0.2 35.3 43.5 70.3
 GLU-1483   LYS-1484  6.3 5.8 -22.2 11.4 136.7 138.0 -98.5
 LYS-1484   GLU-1485  4.3 4.2 -5.0 7.1 76.9 78.0 5.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees