Focal Adhesion Kinase 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-500   LEU-501  10.4 10.7 9.5 -9.6 24.4 23.2 -70.1
 LEU-501   CYS-502  12.4 12.5 0.7 -0.2 64.4 66.9 134.1
 CYS-502   THR-503  10.7 11.2 -2.8 14.8 129.1 127.1 192.1
 THR-503   LEU-504  14.2 14.6 1.7 -7.8 11.9 16.8 -125.3
 LEU-504   GLY-505  13.6 13.7 12.5 -12.2 54.3 50.3 -18.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-559   VAL-560  9.7 9.6 -8.1 9.2 61.8 65.7 39.6
 VAL-560   LYS-561  6.5 6.4 -6.7 11.7 127.6 128.3 -3.1
 LYS-561   LEU-562  3.4 3.6 -5.4 -19.3 58.0 55.3 265.4
 LEU-562   GLY-563  1.7 1.6 -4.5 -42.4 71.9 69.3 189.4
 LEU-562   GLY-563  1.7 1.6 -4.5 -42.4 71.9 69.3 189.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-562   GLY-563  1.7 1.6 -4.5 -42.4 71.9 69.3 189.4
 LEU-562   GLY-563  1.7 1.6 -4.5 -42.4 71.9 69.3 189.4
 GLY-563   ASP-564  5.5 5.3 17.6 -30.2 107.1 60.6 17.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees