Chimera Of Fab2c4: "Humanized" Murine Monoclonal Antibody

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-111   SER-112  6.7 6.4 16.3 -5.3 103.7 101.4 -6.6
 SER-112   SER-113  4.5 4.6 -16.1 20.0 10.1 6.3 -6.0
 SER-113   ALA-114  4.3 5.3 -22.3 8.3 80.2 75.0 39.5
 ALA-114   SER-115  2.2 3.6 -0.4 -19.6 71.4 65.9 38.6
 SER-115   THR-116  2.2 2.7 -13.1 17.1 130.6 116.6 -6.9

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees