Chimeric 48G7 Fab

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-10   LEU-11  6.0 6.2 13.2 -21.0 172.5 155.3 18.5
 LEU-11   PRO-12  4.3 4.6 59.7 -50.2 102.0 90.9 23.5
 PRO-12   VAL-13  4.1 3.7 -5.3 9.1 26.0 14.8 -18.5
 VAL-13   SER-14  2.6 2.5 -13.4 29.6 82.9 85.8 -32.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-108   LEU-109  3.1 3.7 12.5 -37.3 145.7 149.0 51.6
 LEU-109   GLU-110  1.4 1.6 5.7 6.3 73.6 76.3 9.5
 GLU-110   ILE-111  2.5 2.3 -18.0 0.8 35.2 28.4 37.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees