Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-72   ILE-73  7.2 6.0 31.2 22.6 63.1 23.6 227.6
 ILE-73   ARG-74  3.4 3.4 31.9 15.8 81.6 73.4 23.8
 ARG-74   LEU-75  3.6 4.1 -7.6 -4.6 164.5 162.4 -48.7
 LEU-75   GLY-76  4.5 4.4 5.8 -5.7 55.7 53.0 5.9
 GLY-76   ARG-77  5.6 5.7 9.0 -7.4 79.1 74.9 60.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-157   SER-158  2.9 3.3 17.4 -16.7 44.5 51.3 -3.1
 SER-158   LEU-159  2.6 2.6 -5.9 8.7 78.1 79.2 -28.7
 LEU-159   PRO-160  5.2 5.5 25.3 8.1 37.3 32.9 145.5
 PRO-160   GLY-161  7.1 7.1 -4.0 7.6 77.3 83.8 0.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees