Cell Division Protein Kinase 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-34   ILE-35  10.2 10.3 -6.1 -7.1 50.0 50.2 123.2  ILE-35   ARG-36  10.9 10.4 -33.7 12.3 38.7 31.5 259.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  HIS-71   THR-72  3.3 2.9 2.9 28.8 65.6 68.1 82.2  THR-72   GLU-73  6.9 6.5 -170.3 152.6 120.9 147.2 -75.6  GLU-73   ASN-74  8.8 8.3 -164.2 -135.6 95.4 97.2 -108.7  ASN-74   LYS-75  7.5 9.9 -7.4 -26.1 37.4 33.7 279.1  LYS-75   LEU-76  8.6 9.0 11.4 -13.2 118.4 103.3 -32.8  LEU-76   TYR-77  6.0 6.0 -2.3 5.6 9.6 10.3 -55.8  TYR-77   LEU-78  5.5 5.4 18.4 -15.1 116.1 115.7 -62.6  LEU-78   VAL-79  4.1 4.3 -7.7 11.2 159.8 160.3 19.7  LEU-78   VAL-79  4.1 4.3 -7.7 11.2 159.8 160.3 19.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-78   VAL-79  4.1 4.3 -7.7 11.2 159.8 160.3 19.7  LEU-78   VAL-79  4.1 4.3 -7.7 11.2 159.8 160.3 19.7  VAL-79   PHE-80  2.3 2.5 -3.3 4.7 127.5 127.2 -50.7  PHE-80   GLU-81  3.6 4.2 8.8 -17.9 22.8 22.4 9.2  GLU-81   PHE-82  3.1 3.6 19.9 -16.5 68.0 66.0 -67.6  PHE-82   LEU-83  4.8 5.3 6.3 -8.7 33.0 29.2 28.2  LEU-83   HIS-84  7.3 7.6 -6.4 13.7 107.8 108.5 -5.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees