Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-67   LYS-68  6.8 6.7 2.9 2.2 169.7 165.4 -23.9
 LYS-68   GLY-69  7.9 8.0 -8.6 12.1 62.4 60.1 43.9
 GLY-69   PRO-70  5.8 5.8 0.0 5.9 23.5 23.5 -66.0
 PRO-70   GLU-71  6.6 6.4 -12.8 7.1 36.0 51.0 99.5
 GLU-71   ILE-72  5.8 6.0 -16.0 6.5 33.1 31.4 145.6
 ILE-72   ARG-73  6.2 6.4 26.4 -18.5 122.2 110.9 -88.6
 ARG-73   THR-74  8.1 8.4 -13.8 2.8 28.1 26.5 42.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-163   SER-164  8.9 9.0 -2.1 -1.7 20.2 20.6 77.2
 SER-164   ILE-165  10.0 9.7 -0.5 5.0 101.0 99.4 -35.4
 ILE-165   ALA-166  8.2 8.4 0.5 4.7 135.7 137.2 -52.0
 ALA-166   LEU-167  11.0 11.3 0.9 -4.4 118.6 119.1 87.1
 LEU-167   PRO-168  9.5 9.9 10.0 -25.5 165.5 161.8 146.1
 PRO-168   ALA-169  10.5 10.2 -20.8 41.0 61.7 64.6 -97.0
 ALA-169   LEU-170  7.9 7.4 12.4 -6.4 107.5 100.6 75.7
 LEU-170   ALA-171  8.7 9.4 -40.0 21.0 129.9 130.4 -158.4
 ALA-171   GLU-172  10.5 11.0 3.0 10.7 125.1 124.3 44.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees