Glutamate Receptor 4,Glutamate Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-104   LEU-105  5.4 5.3 13.4 -10.6 43.9 43.0 16.5  LEU-105   GLY-106  2.1 2.1 -6.2 -14.1 62.4 62.5 59.4  GLY-106   ILE-107  2.0 2.0 10.6 -2.4 40.9 43.0 24.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  MET-192   ASN-193  3.7 3.1 -1.7 -1.9 58.1 58.5 7.9  ASN-193   GLU-194  1.3 1.2 -4.7 -4.0 67.4 67.6 52.7  GLU-194   TYR-195  2.6 3.0 12.9 -4.1 141.5 132.7 -47.3  TYR-195   THR-196  3.8 3.8 -3.7 2.2 29.8 26.8 3.7  THR-196   GLU-197  1.2 1.0 4.3 -7.8 112.8 111.2 18.2  GLU-197   GLN-198  3.0 3.5 4.2 -13.9 124.7 123.1 35.1  GLN-198   ARG-199  5.1 5.4 25.5 -12.1 148.2 136.9 -94.7  ARG-199   LYS-200  3.3 3.6 6.1 -8.3 134.4 138.8 29.6  LYS-200   PRO-201  2.2 2.6 1.5 15.1 92.9 89.4 5.5  PRO-201   CYS-202  2.2 2.2 -22.3 9.1 127.6 122.7 -27.4  CYS-202   ASP-203  4.3 4.6 -1.9 -5.6 94.5 94.3 9.8  ASP-203   THR-204  6.1 6.3 6.8 -1.5 24.6 25.8 14.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-211   ASP-212  7.6 7.4 0.4 -5.4 31.3 35.3 -27.2  ASP-212   SER-213  4.8 4.8 -0.3 4.4 84.9 84.6 -10.0  SER-213   LYS-214  1.2 1.1 3.1 25.7 72.9 82.2 60.9  LYS-214   GLY-215  3.2 3.6 -10.6 -11.5 59.0 75.8 67.8 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees