Proto-Oncogene Cbl

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-257   TRP-258  4.7 4.8 -3.5 15.9 87.9 90.6 -31.9
 TRP-258   ASN-259  3.8 3.8 -24.2 15.1 19.6 23.9 101.2
 ASN-259   SER-260  4.2 4.1 -5.9 -5.9 70.8 70.9 -3.3
 SER-260   LEU-261  1.4 1.6 27.0 -12.3 65.7 55.7 -15.4
 LEU-261   ALA-262  1.4 1.3 -12.5 -2.6 92.4 89.9 -20.2
 ALA-262   VAL-263  4.0 3.8 31.7 -21.1 145.2 136.2 -31.5
 VAL-263   THR-264  5.5 5.2 -16.5 9.5 29.8 39.0 40.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-268   MET-269  7.8 7.8 -6.3 18.9 84.5 85.2 -34.1
 MET-269   ALA-270  10.9 10.9 -109.7 104.7 39.5 53.8 -55.7
 ALA-270   PHE-271  11.3 10.1 -63.4 34.9 38.7 38.6 216.0
 PHE-271   LEU-272  14.0 12.2 52.4 -28.7 92.2 76.0 -23.7
 LEU-272   THR-273  15.0 14.8 22.5 8.9 149.2 152.2 -109.4
 THR-273   TYR-274  16.4 16.7 -2.1 -8.9 103.5 104.6 -6.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-293   ARG-294  10.0 9.8 -27.8 27.7 74.3 72.8 -60.8
 ARG-294   LEU-295  9.2 9.7 -23.2 -15.6 27.2 35.1 147.4
 LEU-295   SER-296  8.0 8.5 26.7 -64.6 125.5 127.5 120.3
 SER-296   CYS-297  9.7 10.5 -17.7 23.2 54.7 49.5 -9.8
 CYS-297   THR-298  11.6 11.9 9.6 -1.1 166.0 165.0 -101.5
 THR-298   ARG-299  11.4 11.7 0.9 -5.5 104.1 103.3 56.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-300   GLY-301  6.3 6.2 13.5 -25.4 93.4 94.6 82.1
 GLY-301   GLN-302  2.8 2.8 38.0 -32.1 117.7 98.0 -26.3
 GLN-302   TRP-303  4.9 4.6 -14.5 -5.1 38.4 36.3 111.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees