Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-640   ASP-641  6.4 5.7 -24.0 -5.7 101.6 101.5 -6.4
 ASP-641   PHE-642  3.5 2.3 -23.3 -0.7 100.6 121.9 -9.8
 PHE-642   GLY-643  1.2 2.5 -45.0 -41.9 75.5 67.0 54.2
 GLY-643   LEU-644  2.6 3.5 65.5 2.5 53.3 103.3 50.0
 LEU-644   ALA-645  4.3 3.8 145.1 -12.0 81.3 66.2 69.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-662   PRO-663  9.2 11.3 -43.3 17.5 50.9 97.2 22.2
 PRO-663   VAL-664  7.0 8.1 -83.9 -21.3 21.0 52.5 111.1
 VAL-664   LYS-665  7.7 8.1 18.1 -10.4 133.7 134.4 0.6
 LYS-665   TRP-666  6.3 6.3 10.4 1.2 83.4 74.2 -1.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees