Protease (Retropepsin)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-30   THR-31  4.6 4.9 -1.6 7.5 117.0 116.9 54.6
 THR-31   VAL-32  1.1 1.3 -3.5 -1.4 45.2 43.0 63.0
 VAL-32   ILE-33  3.6 3.8 -2.8 7.5 109.1 108.8 27.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-39   GLY-40  11.5 11.8 -1.4 0.9 111.2 108.1 49.9
 GLY-40   ARG-41  10.3 10.7 8.5 -5.2 57.6 60.6 91.1
 ARG-41   TRP-42  7.5 7.8 -4.9 -6.2 54.2 58.6 76.1
 TRP-42   LYS-43  3.8 4.0 -4.9 1.9 129.3 133.8 0.2
 LYS-43   PRO-44  1.3 1.3 4.2 8.2 117.4 114.3 -167.8
 PRO-44   LYS-45  3.0 2.9 -1.5 -5.7 60.8 60.5 96.0
 LYS-45   MET-46  5.5 5.4 4.7 -12.0 106.3 110.8 9.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-54   LYS-55  11.4 11.7 7.4 1.3 58.2 57.0 -16.5
 LYS-55   VAL-56  8.8 8.9 -1.6 -2.1 67.2 59.5 11.0
 VAL-56   ARG-57  5.6 5.7 -2.6 -1.0 127.1 125.0 -9.2
 ARG-57   GLN-58  2.9 2.9 -1.0 -4.0 50.2 51.7 64.2
 GLN-58   TYR-59  0.9 0.8 -1.6 0.6 100.0 98.8 0.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-73   THR-74  7.9 8.0 6.5 -0.5 133.7 125.0 -87.5
 THR-74   VAL-75  5.2 5.1 -5.6 3.3 115.3 115.9 -48.9
 VAL-75   LEU-76  2.6 2.4 -5.6 2.8 40.8 40.5 77.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-82   ASN-83  10.6 10.6 15.4 5.2 73.3 72.3 132.3
 ASN-83   ILE-84  7.5 7.5 -8.4 7.2 55.1 55.8 -17.4
 ILE-84   ILE-85  4.6 4.7 -3.1 1.1 92.9 93.8 46.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees