Genome Polyprotein

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-312   GLN-313  40.6 41.2 4.9 -0.6 65.8 73.9 -38.1  GLN-313   THR-314  38.3 38.8 -10.8 14.2 139.1 144.9 -14.8  SER-319   MET-320  31.4 30.3 20.8 -3.9 26.2 30.5 179.5  MET-320   VAL-321  32.2 31.8 16.6 -9.2 54.1 41.9 93.8  VAL-321   ASN-322  30.3 30.4 22.2 -32.7 56.4 55.3 -33.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-339   GLN-340  27.4 27.4 -58.4 87.3 153.1 160.8 232.2  GLN-340   MET-341  27.3 27.7 -66.0 69.6 123.2 128.1 -16.2  MET-341   ALA-342  25.1 25.4 -115.0 5.5 104.7 94.0 -107.0  ALA-342   MET-343  27.4 28.4 149.4 9.9 69.1 52.5 1082.1  MET-343   THR-344  27.1 30.8 -57.4 -6.9 157.6 159.1 -446.4  THR-344   ASP-345  26.8 31.2 -73.4 40.4 118.4 126.5 -46.9  ASP-345   THR-346  29.4 31.6 -30.3 12.8 138.9 151.4 -96.8  THR-346   THR-347  29.9 34.2 68.9 -21.5 54.5 62.9 165.0  THR-347   PRO-348  33.4 35.1 9.5 -17.4 17.2 31.3 -58.4  PRO-348   PHE-349  33.4 36.7 -8.9 -26.4 105.2 137.6 -173.8  PHE-349   GLY-350  33.5 34.0 56.3 -0.8 107.2 110.2 -235.5  GLY-350   GLN-351  30.4 31.1 -13.9 -2.3 116.1 114.4 -50.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-511   LEU-512  12.5 12.5 31.3 -20.3 89.4 79.3 -17.1  LEU-512   HIS-513  10.0 9.3 28.6 -17.0 40.9 47.4 53.4  HIS-513   LYS-514  8.9 9.4 49.7 -51.3 102.1 114.8 12.4  LYS-514   LEU-515  9.1 9.4 -43.4 25.3 37.3 50.8 105.7  LEU-515   GLY-516  6.6 6.6 -20.9 4.2 109.0 114.3 -25.7  GLY-516   TYR-517  4.0 4.2 -10.0 9.0 88.4 92.5 -19.1  TYR-517   ILE-518  6.9 7.3 -4.8 5.3 23.5 19.9 36.4  ILE-518   LEU-519  7.2 7.6 -17.3 22.6 72.1 69.4 -33.2  LEU-519   ARG-520  4.5 4.8 -4.4 -5.7 121.4 116.4 40.3  ARG-520   ASP-521  6.7 7.0 4.2 8.8 115.3 117.4 -60.9  ARG-520   ASP-521  6.7 7.0 4.2 8.8 115.3 117.4 -60.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ARG-520   ASP-521  6.7 7.0 4.2 8.8 115.3 117.4 -60.9  ARG-520   ASP-521  6.7 7.0 4.2 8.8 115.3 117.4 -60.9  ASP-521   VAL-522  9.7 10.0 -20.6 21.4 31.5 33.5 15.1  VAL-522   SER-523  8.7 8.9 -7.5 -0.1 100.6 105.8 57.4  SER-523   LYS-524  9.6 9.4 -1.6 -3.8 96.3 97.9 -8.6  LYS-524   LYS-525  12.7 12.8 -9.4 20.5 32.0 32.3 -38.8 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  VAL-706   PRO-707  5.0 4.8 -11.0 16.6 96.9 93.4 -26.9  PRO-707   PHE-708  5.2 5.1 -2.2 -1.2 48.8 53.1 16.4  PHE-708   CYS-709  4.0 3.9 17.1 -12.4 71.8 72.5 78.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees