Bifunctional Dihydrofolate Reductase-Thymidylate Synthase
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
PRO-9
GLU-10
35.1
34.6
-7.8
-4.2
23.0
14.8
117.3
GLU-10
THR-11
34.3
34.5
-24.0
-20.6
87.0
73.4
84.7
THR-11
VAL-12
30.8
30.9
133.9
-19.7
66.7
48.8
603.2
VAL-12
ALA-13
29.9
27.4
-162.2
19.6
80.1
120.9
-581.8
ALA-13
GLU-14
26.8
26.9
148.0
23.8
84.1
109.1
-205.5
GLU-14
GLY-15
25.6
26.2
-19.5
31.3
162.8
111.9
85.9
GLY-15
THR-16
23.4
22.4
-11.6
57.9
108.5
83.2
-3.8
THR-16
ARG-17
22.6
21.3
175.5
-64.2
139.0
145.3
-773.6
ARG-17
LEU-18
21.1
18.4
13.0
4.3
82.7
113.8
108.5
LEU-18
ALA-19
17.4
17.5
11.9
23.9
129.2
60.8
234.8
ALA-19
LEU-20
15.4
16.1
172.6
34.5
111.6
110.7
623.9
LEU-20
ARG-21
12.0
12.4
2.7
-3.8
67.9
71.7
-36.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-193
PRO-194
7.4
8.2
-9.5
-0.2
41.8
41.7
73.4
PRO-194
GLU-195
7.7
8.3
-7.9
-2.3
21.5
25.0
118.4
GLU-195
SER-196
8.3
8.7
-12.5
-13.7
52.3
52.1
223.5
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-204
GLU-205
2.7
3.1
4.7
3.9
62.2
57.7
38.9
GLU-205
TRP-206
1.7
1.9
-5.1
2.1
65.3
65.1
18.0
TRP-206
GLN-207
4.0
4.0
-1.8
14.3
126.1
127.4
54.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
PRO-232
ARG-233
3.7
3.3
18.5
-20.3
154.1
145.1
29.6
ARG-233
ASN-234
4.0
3.8
0.5
9.0
98.5
93.0
39.6
ASN-234
ARG-235
6.7
6.6
-3.1
17.7
13.0
16.1
-133.0
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees