Cyclin-Dependent Kinase 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-21   ARG-22  16.9 16.6 -10.5 20.2 25.9 39.5 -17.4
 ARG-22   ASN-23  17.5 17.0 -13.0 6.5 100.7 109.8 -17.9
 ASN-23   LYS-24  16.4 14.9 -3.6 5.1 70.1 75.1 0.2
 LYS-24   LEU-25  19.9 18.0 2.5 0.8 132.2 123.5 13.8
 LEU-25   THR-26  19.3 16.7 -8.3 18.9 27.4 18.4 -42.8
 THR-26   GLY-27  16.8 14.8 -6.5 1.4 73.7 68.0 5.1
 GLY-27   GLU-28  17.9 17.1 3.1 -19.3 90.4 105.1 12.6
 GLU-28   VAL-29  14.5 14.4 7.5 5.4 43.1 43.6 35.1
 VAL-29   VAL-30  15.2 15.3 1.8 1.5 64.7 82.1 5.1
 VAL-30   ALA-31  12.9 12.6 -6.1 20.6 141.4 135.7 27.9
 ALA-31   LEU-32  12.7 12.5 -5.0 -0.7 134.4 138.7 -12.5
 LEU-32   LYS-33  11.6 11.4 -5.3 -9.6 139.9 134.4 -31.1
 LYS-33   LYS-34  10.4 10.6 -2.8 13.3 135.5 146.9 26.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-55   LYS-56  6.2 6.3 10.4 4.9 53.0 55.4 49.1
 LYS-56   GLU-57  4.0 2.9 -13.4 9.4 131.2 153.5 -42.2
 GLU-57   LEU-58  7.2 5.4 -21.1 19.4 134.8 130.9 -3.7
 LEU-58   ASN-59  7.5 7.1 18.5 -3.9 53.4 66.7 51.8
 ASN-59   HIS-60  5.2 5.3 28.8 -1.2 39.8 39.1 68.4
 HIS-60   PRO-61  7.6 7.6 -1.6 2.5 99.0 100.5 -3.6
 PRO-61   ASN-62  8.6 8.4 4.8 -3.9 121.8 117.8 2.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees