Epidermal Growth Factor Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  CYS-302   LYS-303  11.4 9.7 33.4 -2.9 112.2 92.9 -5.3  LYS-303   LYS-304  9.5 9.1 -26.6 26.7 137.5 151.6 -0.4  LYS-304   CYS-305  9.3 9.6 10.5 -23.7 91.0 90.2 16.5  CYS-305   GLU-306  6.9 7.3 72.5 0.5 83.0 59.5 29.6  GLU-306   GLY-307  10.0 9.0 104.9 155.4 56.0 13.0 167.6  GLY-307   PRO-308  9.3 9.2 64.4 5.5 45.7 79.9 -211.7  PRO-308   CYS-309  8.2 5.9 4.1 -64.6 93.2 138.5 28.5  CYS-309   ARG-310  4.5 3.4 51.7 -14.1 67.1 72.4 0.2  ARG-310   LYS-311  3.4 0.8 -36.7 157.4 147.1 123.7 75.1  LYS-311   VAL-312  3.6 2.9 -2.0 -45.0 94.6 76.8 2.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees