Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  7.7 7.2 4.8 8.6 146.9 145.4 -14.8
 ALA-640   ASP-641  5.5 5.1 -24.8 -1.0 101.2 100.8 -3.1
 ASP-641   PHE-642  2.8 2.1 -39.8 10.5 105.2 120.2 -9.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  13.1 14.0 7.3 37.9 116.1 103.2 -5.0
 LEU-662   PRO-663  10.4 12.9 -45.2 17.7 54.1 92.4 28.5
 PRO-663   VAL-664  8.3 9.5 -91.2 -12.0 15.7 48.1 125.6
 VAL-664   LYS-665  9.2 9.7 18.0 -7.7 133.7 137.8 -3.6
 LYS-665   TRP-666  8.0 8.2 7.5 4.0 87.4 80.2 -4.0
 TRP-666   MET-667  4.4 4.8 1.3 9.8 94.6 92.1 3.9
 MET-667   ALA-668  5.2 5.5 -9.3 16.3 24.5 31.4 -7.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees