Nicotinamide Phosphoribosyltransferase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-241   VAL-242  11.3 11.6 -26.4 25.5 102.3 108.0 54.1
 VAL-242   PRO-243  7.7 8.0 4.7 -5.2 36.4 36.6 -12.9
 PRO-243   ALA-244  5.8 6.1 8.4 -24.5 107.3 103.7 15.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-310   ARG-311  7.0 6.7 2.4 -35.3 84.2 86.6 -58.9
 ARG-311   PRO-312  9.8 9.2 7.0 -49.4 89.6 115.1 -56.4
 PRO-312   ASP-313  12.9 12.9 2.4 -96.0 132.7 95.0 544.8
 ASP-313   SER-314  16.2 15.7 -144.0 7.8 99.7 70.2 -9.6
 SER-314   GLY-315  19.1 18.6 140.6 42.7 48.9 63.4 -889.3
 GLY-315   ASN-316  21.7 21.3 -83.5 142.2 137.9 173.8 502.3
 ASN-316   PRO-317  21.8 21.8 -42.7 4.0 102.7 111.6 -86.0
 PRO-317   LEU-318  18.9 18.6 2.4 11.1 40.9 34.5 97.3
 LEU-318   ASP-319  18.2 18.9 -17.5 2.0 81.0 82.2 24.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-328   GLY-329  12.0 12.4 0.7 -2.1 147.3 147.2 16.4
 GLY-329   LYS-330  12.5 12.6 5.9 -10.1 90.9 87.3 13.9
 LYS-330   LYS-331  16.0 16.1 1.9 -0.1 56.4 47.2 3.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-332   PRO-333  12.3 12.6 -4.1 3.5 173.7 175.0 1.7
 PRO-333   VAL-334  11.8 12.5 -15.6 21.2 116.1 119.2 8.9
 VAL-334   SER-335  9.6 10.3 2.0 8.6 21.8 25.9 101.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-346   TYR-347  4.3 4.3 12.3 -14.4 7.7 5.5 -15.2
 TYR-347   LEU-348  4.8 4.8 10.2 -11.4 70.6 69.4 15.2
 LEU-348   ARG-349  3.8 4.2 -4.9 -1.0 61.9 59.3 22.2
 ARG-349   VAL-350  3.3 3.7 -1.8 -2.9 58.9 53.2 46.2
 ARG-349   VAL-350  3.3 3.7 -1.8 -2.9 58.9 53.2 46.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-349   VAL-350  3.3 3.7 -1.8 -2.9 58.9 53.2 46.2
 ARG-349   VAL-350  3.3 3.7 -1.8 -2.9 58.9 53.2 46.2
 VAL-350   ILE-351  6.7 7.0 1.6 5.7 93.2 90.4 16.0
 ILE-351   GLN-352  8.9 9.2 7.7 20.9 102.0 104.3 -60.2
 GLN-352   GLY-353  12.7 13.0 0.3 32.9 110.9 134.1 -164.4
 GLY-353   ASP-354  14.7 14.1 -48.9 -9.5 74.7 89.0 66.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees