Alcohol Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-175   PHE-176  2.9 2.8 2.4 -5.3 89.5 88.4 10.8
 PHE-176   SER-177  0.8 1.0 -0.9 -1.2 29.8 30.7 28.6
 SER-177   THR-178  2.9 3.2 3.4 -2.8 136.4 139.5 -24.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-288   SER-289  14.1 14.1 -2.2 -2.2 47.7 51.0 22.8
 SER-289   VAL-290  12.6 12.6 -2.7 10.5 90.0 93.3 20.8
 VAL-290   ILE-291  9.0 9.0 2.0 12.4 117.6 112.6 -126.9
 ILE-291   SER-292  8.2 8.6 -28.4 22.1 70.0 60.3 127.8
 SER-292   GLY-293  5.9 6.6 -26.0 65.3 76.6 76.9 -93.7
 GLY-293   VAL-294  8.7 9.6 25.5 51.9 42.2 47.7 756.8
 VAL-294   PRO-295  10.8 10.8 9.9 -20.9 100.0 76.5 60.8
 PRO-295   PRO-296  13.7 13.9 22.3 -6.7 33.3 90.4 33.8
 PRO-296   ASP-297  14.6 17.3 167.9 47.4 59.9 27.7 -1569.0
 ASP-297   SER-298  17.8 17.6 110.7 119.2 72.1 39.3 1888.9
 SER-298   GLN-299  16.6 18.2 -117.1 -26.9 150.1 95.1 -894.5
 GLN-299   ASN-300  18.8 19.0 -40.5 -23.1 118.7 114.2 -236.5
 ASN-300   LEU-301  17.7 18.0 4.9 -6.5 114.9 110.8 30.9
 LEU-301   SER-302  17.9 18.2 0.3 -4.3 38.3 33.1 -85.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-317   ILE-318  1.4 1.7 -5.7 5.1 48.8 46.6 4.6
 ILE-318   PHE-319  2.8 2.8 -9.3 3.2 56.0 52.6 112.0
 PHE-319   GLY-320  2.9 2.6 0.0 -3.5 90.8 88.1 -45.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees