Aldose Reductase
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ALA-208
TYR-209
12.5
12.5
8.7
-9.1
20.9
20.8
-18.2
TYR-209
SER-210
14.6
14.2
2.9
-8.3
56.9
66.3
12.6
SER-210
PRO-211
14.3
13.8
14.5
-12.1
101.3
110.3
-9.1
PRO-211
LEU-212
10.7
10.5
21.5
-7.2
48.8
58.1
16.0
LEU-212
GLY-213
10.4
10.9
-5.4
-19.0
106.3
95.3
-28.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-236
ALA-237
10.6
10.4
-5.7
1.9
59.9
57.2
3.8
ALA-237
ALA-238
7.9
8.1
-16.2
-2.2
63.5
69.0
33.6
ALA-238
LYS-239
10.8
11.2
11.0
3.3
56.8
47.2
21.2
LYS-239
HIS-240
11.9
12.3
-12.1
2.8
99.8
97.2
-11.3
HIS-240
ASN-241
8.9
9.6
12.9
-2.1
151.1
146.3
-54.2
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-249
ARG-250
4.4
4.2
-1.6
-9.3
142.2
148.1
-40.0
ARG-250
PHE-251
1.4
1.4
14.2
-10.7
38.9
38.8
24.0
PHE-251
PRO-252
4.3
3.9
4.1
5.0
46.3
48.2
30.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-258
VAL-259
10.5
10.4
3.7
-12.2
41.8
42.4
-15.3
VAL-259
ILE-260
9.8
9.9
-13.7
20.4
135.9
144.5
74.6
ILE-260
PRO-261
12.2
12.2
28.0
-5.3
30.5
45.5
47.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-265
PRO-266
10.6
10.7
34.4
-11.7
68.7
75.8
47.6
PRO-266
GLU-267
11.0
10.2
16.4
-6.8
73.5
70.7
18.5
GLU-267
ARG-268
7.5
6.5
-2.9
7.8
150.7
166.8
21.5
ARG-268
ILE-269
6.5
6.8
2.8
-9.0
34.0
51.5
-24.5
ILE-269
ALA-270
9.4
9.4
-6.3
3.4
111.1
99.3
-18.0
ALA-270
GLU-271
8.5
8.1
1.4
-8.4
67.1
58.6
-8.3
GLU-271
ASN-272
4.7
4.4
-5.5
3.1
158.4
168.7
-8.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
PHE-276
ASP-277
6.9
7.4
-16.4
21.4
85.5
80.5
13.8
ASP-277
PHE-278
8.4
9.0
-33.6
33.3
88.9
75.5
4.1
PHE-278
GLU-279
7.0
7.3
1.7
6.8
138.5
139.7
13.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-280
SER-281
5.9
5.7
4.7
-10.2
31.5
27.4
-12.6
SER-281
SER-282
8.8
8.4
4.4
2.5
53.5
59.2
9.6
SER-282
GLN-283
8.9
8.9
-2.9
7.2
69.5
62.4
-19.5
GLN-283
ASP-284
11.9
11.9
-8.6
5.5
38.2
39.4
26.1
ASP-284
MET-285
9.9
9.7
-2.4
-4.2
112.1
109.1
9.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees