S-Adenosyl-L-Homocysteine Hydrolase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-184   LYS-185  2.1 2.0 -29.5 20.6 108.2 110.1 -8.0  LYS-185   SER-186  4.8 4.2 29.2 0.9 96.9 103.2 -13.9  SER-186   LYS-187  7.8 6.7 -7.6 15.0 102.5 118.9 -8.3  LYS-187   PHE-188  8.0 7.5 -18.3 31.6 167.1 159.2 86.4  PHE-188   ASP-189  7.3 7.2 -4.3 12.0 121.5 96.2 49.9  ASP-189   ASN-190  8.2 9.2 35.0 -38.1 101.0 105.2 8.6  ASN-190   LEU-191  11.5 11.6 -38.7 12.8 97.6 109.8 -42.0  LEU-191   TYR-192  12.2 12.3 -5.4 14.8 159.7 168.8 46.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  PRO-353   SER-354  9.2 9.0 6.4 -2.0 74.3 76.2 20.3  SER-354   PHE-355  6.3 6.1 -10.3 4.5 118.9 130.5 5.9  PHE-355   VAL-356  4.0 3.8 21.1 -9.5 6.7 15.2 65.2  VAL-356   MET-357  5.5 5.7 -13.4 8.5 109.6 103.8 9.5  MET-357   SER-358  6.1 6.4 -6.5 4.8 95.3 95.2 31.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  VAL-382   HIS-383  12.5 12.7 -28.2 20.5 80.7 78.2 39.6  HIS-383   PHE-384  9.7 9.9 -16.0 30.4 136.3 137.2 59.1  PHE-384   LEU-385  6.6 6.6 -9.3 21.5 113.7 123.7 11.0  LEU-385   PRO-386  6.5 6.6 -13.7 -6.9 71.6 69.5 0.9  PRO-386   LYS-387  7.3 7.2 4.4 -2.7 118.8 125.5 8.3  PRO-386   LYS-387  7.3 7.2 4.4 -2.7 118.8 125.5 8.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  PRO-386   LYS-387  7.3 7.2 4.4 -2.7 118.8 125.5 8.3  PRO-386   LYS-387  7.3 7.2 4.4 -2.7 118.8 125.5 8.3  LYS-387   LYS-388  5.6 5.6 -6.7 5.1 39.5 44.5 36.8  LYS-388   LEU-389  8.7 8.9 4.9 -4.6 147.9 149.8 -27.0  LEU-389   ASP-390  7.4 7.8 10.9 -14.1 112.2 112.2 14.0  ASP-390   GLU-391  3.8 4.2 10.2 -9.2 124.5 119.3 -10.4  GLU-391   ALA-392  6.3 6.7 3.9 -4.3 152.9 154.4 11.4  ALA-392   VAL-393  7.5 7.9 -1.5 -8.2 47.6 42.0 46.4  VAL-393   ALA-394  4.1 4.7 12.8 5.6 115.4 107.8 -94.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees