Potassium/sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 11

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-540   ILE-541  9.2 8.0 12.6 -0.8 36.0 29.4 55.7
 ILE-541   CYS-542  9.6 9.1 -10.3 41.2 106.0 121.1 40.3
 CYS-542   LEU-543  5.8 5.8 -110.2 51.3 38.0 65.4 112.4
 LEU-543   LEU-544  5.2 4.5 18.7 36.9 67.6 76.2 75.7
 LEU-544   THR-545  7.2 8.1 -42.2 -17.6 4.6 18.0 216.4
 LEU-544   THR-545  7.2 8.1 -42.2 -17.6 4.6 18.0 216.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-544   THR-545  7.2 8.1 -42.2 -17.6 4.6 18.0 216.4
 LEU-544   THR-545  7.2 8.1 -42.2 -17.6 4.6 18.0 216.4
 THR-545   LYS-546  6.3 7.6 25.1 -8.2 111.4 112.7 -9.0
 LYS-546   GLY-547  3.3 4.4 -22.4 41.0 31.7 34.2 -53.8
 GLY-547   ARG-548  1.6 4.1 15.1 -27.9 77.6 74.5 3.3
 ARG-548   ARG-549  4.1 5.1 20.6 15.5 67.9 57.5 72.6
 ARG-549   THR-550  7.2 8.2 -12.7 -9.2 49.4 53.5 62.0
 THR-550   ALA-551  10.4 11.2 53.6 -54.4 82.8 85.1 -57.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-563   LEU-564  6.5 6.4 9.3 0.9 101.8 102.3 -2.8
 LEU-564   SER-565  2.9 2.8 15.0 -3.2 29.4 28.3 48.9
 SER-565   VAL-566  2.0 1.6 10.3 3.0 71.5 64.4 22.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees