Alcohol Dehydrogenase (Holo Form) (E.C.1.1.1.1)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-92   PHE-93  8.1 8.1 3.9 -6.0 120.0 116.4 76.8  PHE-93   THR-94  8.8 8.8 9.4 0.7 172.3 175.2 -98.0  THR-94   PRO-95  7.2 7.6 17.9 -18.3 96.4 91.5 126.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-112   LYS-113  10.0 10.2 6.3 5.0 119.0 122.6 15.9  LYS-113   ASN-114  12.7 12.9 -23.9 31.6 32.0 42.7 -43.5  LEU-116   SER-117  13.7 14.6 129.4 -21.3 37.0 110.1 546.3  SER-117   MET-118  14.5 14.5 -102.9 75.9 97.1 66.8 219.8  MET-118   PRO-119  18.0 17.4 -117.8 -21.7 40.4 106.3 -996.0  PRO-119   ARG-120  18.8 20.2 -142.0 -2.8 90.5 80.7 -64.7  ARG-120   GLY-121  21.1 19.6 110.9 -138.5 162.3 159.0 455.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-175   PHE-176  5.9 5.7 0.7 12.0 99.2 98.9 -3.2  PHE-176   SER-177  4.7 4.8 -6.8 7.1 24.8 22.4 -26.3  SER-177   THR-178  3.2 3.3 -3.6 -2.5 45.5 42.7 41.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-316   ALA-317  10.1 10.5 7.8 3.6 100.6 100.9 -5.6  ALA-317   ILE-318  6.8 7.2 -7.4 13.1 43.3 37.3 -92.6  ILE-318   PHE-319  5.8 5.9 14.1 -20.5 120.1 120.7 133.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLU-366   SER-367  17.6 18.1 -120.7 29.6 124.5 85.6 -278.5  SER-367   ILE-368  14.2 14.5 67.8 -40.1 144.0 153.8 -348.5  ILE-368   ARG-369  12.4 12.3 -33.5 39.6 72.0 83.2 -104.0  ARG-369   THR-370  9.4 9.2 0.0 13.0 34.0 23.8 152.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees