Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-637   LYS-638  14.0 13.6 -5.3 -3.3 52.6 57.8 3.7
 LYS-638   ILE-639  11.4 10.8 6.9 -5.9 78.7 79.0 1.1
 ILE-639   ALA-640  7.9 7.2 8.7 15.3 149.0 142.2 -23.3
 ALA-640   ASP-641  5.4 4.8 -12.7 -15.5 99.4 97.1 3.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  12.7 14.3 26.5 37.6 120.2 78.4 -19.9
 LEU-662   PRO-663  10.1 12.6 -11.1 15.9 55.9 86.5 3.2
 PRO-663   VAL-664  8.0 9.1 -91.3 -11.2 12.1 39.7 108.7
 VAL-664   LYS-665  9.2 9.5 17.8 -5.2 134.6 138.0 -4.8
 LYS-665   TRP-666  8.1 8.3 -10.0 15.5 88.3 94.3 -5.4
 TRP-666   MET-667  4.4 4.8 -7.4 12.7 81.8 82.4 -0.7
 MET-667   ALA-668  5.4 5.6 -0.5 -2.1 20.9 24.4 2.8
 ALA-668   PRO-669  5.8 5.6 13.8 -26.5 102.7 106.2 4.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees