Pyruvate Kinase Isozymes M1/m2
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ILE-118
ARG-119
6.1
6.8
13.4
-19.7
93.5
87.9
1.7
ARG-119
THR-120
3.3
3.8
2.3
-11.8
86.9
83.2
4.4
THR-120
GLY-121
1.2
0.8
34.1
-0.8
33.8
35.5
158.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ALA-129
GLU-130
13.9
13.8
-167.4
47.2
144.7
153.2
-622.1
GLU-130
VAL-131
13.1
13.6
-30.3
30.1
110.6
102.4
1.9
VAL-131
GLU-132
13.0
13.5
58.1
-13.6
25.3
17.5
264.3
GLU-132
LEU-133
12.9
13.8
-6.6
17.6
98.8
94.6
24.3
LEU-133
LYS-134
11.7
10.9
-6.6
-5.1
172.2
141.9
-55.9
LYS-134
LYS-135
12.7
12.4
-64.4
19.2
114.0
130.1
-143.8
LYS-135
GLY-136
10.4
10.3
-16.8
20.4
104.9
111.1
-18.0
GLY-136
ALA-137
11.6
11.1
-80.1
82.3
42.6
30.7
-38.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-142
LEU-143
9.9
9.7
15.6
-3.4
53.5
51.4
52.6
LEU-143
ASP-144
9.2
8.4
-9.7
-10.7
154.0
159.2
-92.3
ASP-144
ASN-145
10.1
9.3
-128.7
133.8
111.9
104.1
-62.3
ASN-145
ALA-146
7.1
7.2
107.7
-45.0
70.2
77.7
107.8
ALA-146
TYR-147
9.3
10.3
-26.7
-9.4
50.3
77.7
140.9
TYR-147
MET-148
8.7
10.0
45.9
-17.2
94.1
81.1
55.9
MET-148
GLU-149
5.3
7.1
-13.9
23.6
85.9
87.9
-2.0
GLU-149
LYS-150
7.8
9.6
-9.3
19.1
45.5
34.4
-67.1
LYS-150
CYS-151
10.3
11.3
34.6
-24.3
37.3
36.5
9.6
LYS-150
CYS-151
10.3
11.3
34.6
-24.3
37.3
36.5
9.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LYS-150
CYS-151
10.3
11.3
34.6
-24.3
37.3
36.5
9.6
LYS-150
CYS-151
10.3
11.3
34.6
-24.3
37.3
36.5
9.6
CYS-151
ASP-152
9.2
9.6
-74.5
26.8
124.3
139.5
-143.8
ASP-152
GLU-153
11.7
12.1
-20.5
14.3
162.5
130.3
-23.7
GLU-153
ASN-154
12.1
11.6
86.6
-61.4
81.7
103.7
38.3
ASN-154
ILE-155
13.3
12.6
-20.8
-17.9
61.1
61.1
93.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-156
TRP-157
7.2
6.6
-0.2
-2.1
54.9
67.4
27.7
TRP-157
LEU-158
5.4
5.1
23.7
0.7
80.9
83.9
-21.0
LEU-158
ASP-159
3.4
3.8
5.3
-6.5
138.8
142.4
21.9
ASP-159
TYR-160
4.4
5.2
-31.5
29.8
99.2
102.8
18.7
TYR-160
LYS-161
7.8
8.4
7.9
18.0
91.2
100.5
48.7
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-196
GLU-197
8.2
7.4
-1.9
-3.1
11.7
16.8
24.5
GLU-197
ASN-198
6.2
5.1
17.5
-35.2
105.2
99.7
2.4
ASN-198
GLY-199
4.8
5.0
-140.9
164.0
115.0
131.4
120.8
GLY-199
GLY-200
7.1
8.4
-39.7
45.8
93.3
104.1
28.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLY-203
SER-204
9.1
8.9
34.8
-65.9
137.2
146.9
188.8
SER-204
LYS-205
7.6
7.3
-19.9
11.7
85.0
73.8
34.6
LYS-205
LYS-206
5.1
4.8
-6.5
0.3
140.3
138.1
4.1
LYS-206
GLY-207
5.1
5.2
2.4
1.7
81.4
71.3
54.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees