Pyruvate Kinase, M2 Isozyme

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-117   GLU-118  14.4 14.3 0.2 26.0 57.2 53.1 221.5
 GLU-118   ILE-119  11.9 12.0 16.9 -27.2 48.0 67.9 -189.8
 ILE-119   ARG-120  11.1 11.1 -0.6 3.3 149.5 151.2 124.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-162   ASN-163  18.5 18.6 -21.8 14.0 139.3 134.3 -32.8
 ASN-163   ILE-164  18.9 17.9 -23.2 5.1 96.8 85.2 128.7
 ILE-164   CYS-165  15.8 14.8 0.6 6.2 75.3 86.8 124.7
 CYS-165   LYS-166  18.0 17.4 -4.3 -12.0 161.7 156.5 -215.9
 LYS-166   VAL-167  19.1 18.5 6.4 -2.7 47.6 46.1 46.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-168   GLU-169  14.2 13.6 -45.4 45.3 85.0 91.5 -19.4
 GLU-169   VAL-170  16.1 16.1 -9.2 23.2 135.4 128.6 88.9
 VAL-170   GLY-171  17.6 17.6 7.0 -21.7 109.1 110.7 41.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-211   PRO-212  7.0 6.6 7.9 -20.8 25.8 21.5 -81.5
 PRO-212   GLY-213  5.0 4.8 14.1 21.5 49.7 61.9 258.9
 GLY-213   ALA-214  6.9 7.1 -71.5 48.8 76.4 87.0 -14.0
 ALA-214   ALA-215  9.6 9.5 6.5 -5.8 69.4 66.2 -25.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees