3C-Like Protease

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 3C-Like Protease
  Conformer 1
(PDB)
4in1 (A)
  Conformer 2
(PDB)
4inh (C)
  Window Length 13
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 132 0.73   6 - 99   122 - 167
2 22 0.96   100 - 121

Sequence


           __________________________________________________________________________________________________99___________________1 
 4in1(A) : SAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHGQSG 
         :                                                                                                                          
 4inh(C) : KAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHGQSG 
           __________________________________________________________________________________________________99___________________1 

           21____________________________________________________                                                                   
 4in1(A) : MLLTlGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQAGEGEINFE                                                                   
         :                                                                                                                          
 4inh(C) : MLLdLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQA********                                                                   
           21____________________________________________________                                                                   

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
9.1
Translation
(A)
0.2
Closure
(%)
68.6
Bending Residues
( green )
  99 - 100
  121 - 135
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download