Bromodomain Phd Finger Transcription Factor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Bromodomain Phd Finger Transcription Factor
  Conformer 1
(PDB)
2f6n (B)
  Conformer 2
(PDB)
2f6j (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 20 0.44   10 - 10   25 - 32   51 - 61
2 32 0.38   11 - 24   33 - 50
3 99 0.69   66 - 168

Sequence


           __10____________24______32______________48___________61_________________________________________________________________ 
 2f6n(B) : *KLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAtVLTPLTEKDYEGLKRVLRSLQAHKaWPFLEPVDPNDAPDYYGVIKEPdLATeERVQRRYYEKL 
         :                                                                                                                          
 2f6j(B) : TKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAtVLTPLTEKDYEGLKRVLRSLQAHKaWPFLEPVDPNDAPDYYGVIKEPdLATeERVQRRYYEKL 
           __10____________24______32______________48___________61_________________________________________________________________ 

           __________________________________________                                                                               
 2f6n(B) : TEFVADtKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK***                                                                               
         :                                                                                                                          
 2f6j(B) : TEFVADtKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFK                                                                               
           __________________________________________                                                                               

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
7.5
Translation
(A)
0.3
Closure
(%)
85.3
Bending Residues
( green )
  10 - 11
  24 - 25
  32 - 33
  48 - 51
Bending Region Analysis
Property Value
Fixed Domain
( blue )
1
Moving Domain
( yellow )
3
Rotation Angle
(deg)
23.2
Translation
(A)
-1.6
Closure
(%)
82.2
Bending Residues
( green )
  61 - 67
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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