Elongation Factor 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Elongation Factor 2
  Conformer 1
(PDB)
1n0v (D)
  Conformer 2
(PDB)
1zm9 (C)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 483 0.68   4 - 482   731 - 732   734 - 735   759 - 763   765 - 765   785 - 796
2 82 0.98   483 - 559   729 - 730   772 - 773   779 - 779
3 249 0.81   563 - 728   733 - 733   736 - 758   764 - 764   766 - 770   774 - 778   780 - 784   797 - 840

Sequence


           ________________________________________________________________________________________________________________________ 
 1n0v(D) : VAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKgITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCV 
         :                                                                                                                          
 1zm9(C) : VAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISA--gITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCV 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1n0v(D) : QTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYADEVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFGVDKAKMMDRLWGDSFFNPKTKKW 
         :                                                                                                                          
 1zm9(C) : QTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYADEVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFGVDKAKMMDRLWGDSFFNPKTKKW 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1n0v(D) : TNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDPKAD 
         :                                                                                                                          
 1zm9(C) : TNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDPKAD 
           ________________________________________________________________________________________________________________________ 

           ______________________________________________________________________________________________________482_______________ 
 1n0v(D) : LMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKN 
         :                                                                                                                          
 1zm9(C) : LMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKN 
           ______________________________________________________________________________________________________482_______________ 

           ___________________________________________________________559__________________________________________________________ 
 1n0v(D) : ANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARAR 
         :                                                                                                                          
 1zm9(C) : ANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARAR 
           ___________________________________________________________559__________________________________________________________ 

           ______________________________________________________________________________________________________________730_______ 
 1n0v(D) : IMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPE 
         :                                                                                                                          
 1zm9(C) : IMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAI-rGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPE 
           ______________________________________________________________________________________________________________730_______ 

           __________________758__763____770_____778___784_________796______________________________________________                
 1n0v(D) : QAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL                
         :                                                                                                                          
 1zm9(C) : QAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL                
           __________________758__763____770_____778___784_________796______________________________________________                

Morph

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Status: Initialising

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Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 11.7 0.0 12.4   482 - 483   730 - 731 Bending Region Analysis
1 3 8.7 -0.5 22.7   732 - 737   758 - 759   763 - 766   784 - 785   796 - 797 Bending Region Analysis
2 3 9.7 0.0 70.1   559 - 563   728 - 729   770 - 774   778 - 780 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 2 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 2

Movement classification:

No Contacts

PyMOL Script

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