Apoptosis Regulator Bcl-X

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Apoptosis Regulator Bcl-X
  Conformer 1
(PDB)
2b48 (A)
  Conformer 2
(PDB)
2p1l (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 75 2.35   83 - 157
2 39 1.53   158 - 196

Sequence


           __________________________________________________________________________________________________157___________________ 
 2b48(A) : MSQSNRELVVDFLSYKLSQKGYSWp-MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLND 
         :                                                                                                                          
 2p1l(A) : *SQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLND 
           __________________________________________________________________________________________________157___________________ 

           ________________________                                                                                                 
 2b48(A) : HLEPWIQENGGWDTFVELYGNNAA                                                                                                 
         :                                                                                                                          
 2p1l(A) : HLEPWIQENGGWDTFVELYGNN**                                                                                                 
           ________________________                                                                                                 

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
176.1
Translation
(A)
-2.3
Closure
(%)
99.8
Bending Residues
( green )
  157 - 159
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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