DNA Polymerase Iota

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name DNA Polymerase Iota
  Conformer 1
(PDB)
2dpj (A)
  Conformer 2
(PDB)
1zet (A)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 337 1.61   32 - 304   308 - 343   360 - 394   409 - 409
2 24 2.2   305 - 307   344 - 359   404 - 408

Sequence


           ________________________________________________________________________________________________________________________ 
 2dpj(A) : ASSRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQ 
         :                                                                                                                          
 1zet(A) : **SRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQ 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2dpj(A) : SDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTF 
         :                                                                                                                          
 1zet(A) : SDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTF 
           ________________________________________________________________________________________________________________________ 

           _____________________________________304_________________________________340________________359_________________________ 
 2dpj(A) : SPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQ--------vMTPMV 
         :                                                                                                                          
 1zet(A) : SPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMV 
           _____________________________________304_________________________________340________________359_________________________ 

           __389________________408______                                                                                           
 2dpj(A) : DILMKLFRNM---------tLLSVCFCNLK                                                                                           
         :                                                                                                                          
 1zet(A) : DILMKLFRNMVNVKMPFHLTLLSVCFCNLK                                                                                           
           __389________________408______                                                                                           

Morph

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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
16.7
Translation
(A)
-0.6
Closure
(%)
99.3
Bending Residues
( green )
  304 - 332
  340 - 344
  359 - 360
  389 - 404
  408 - 409
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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