Atp-Dependent RNA Helicase Ddx3x

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Atp-Dependent RNA Helicase Ddx3x
  Conformer 1
(PDB) 		2i4i (A)
  Conformer 2
(PDB) 		5e7j (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 231 1.75   169 - 411
2 165 1.03   412 - 578

Sequence


           ________________________________________________________________________________________________________________________ 
 2i4i(A) : ***********************MVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRR 
         :                                                                                                                          
 5e7j(A) : EDDWSKPLPPSERLEQELFSGGiPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMK-------- 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2i4i(A) : KQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSA 
         :                                                                                                                          
 5e7j(A) : kQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSA 
           ________________________________________________________________________________________________________________________ 

           __________________404___________________________________________________________________________________________________ 
 2i4i(A) : TFPKEIQMLARDFLDEYIFLAVG----tSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAAR 
         :                                                                                                                          
 5e7j(A) : TFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAAR 
           __________________404___________________________________________________________________________________________________ 

           _________________________________________________________________________________                                        
 2i4i(A) : GLDISNVKHVINFDLPSDIEEYVHRIGRTGR--nLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHY****                                        
         :                                                                                                                          
 5e7j(A) : GLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS                                        
           _________________________________________________________________________________                                        

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		179.5
Translation
(A) 		-6.5
Closure
(%) 		38.4
Bending Residues
( green ) 		  404 - 414
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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