Carminomycin 4-O-Methyltransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Carminomycin 4-O-Methyltransferase
  Conformer 1
(PDB) 		1tw2 (A)
  Conformer 2
(PDB) 		1tw2 (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 192 1.22   114 - 115   121 - 121   130 - 283   310 - 311   317 - 349
2 141 0.71   17 - 113   116 - 120   122 - 129   284 - 309   312 - 316

Sequence


           ____________________________________________________________________________________________________________113____120__ 
 1tw2(A) : ***********DALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRL 
         :                                                                                                                          
 1tw2(B) : EPTVAARPQQIDALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRL 
           ____________________________________________________________________________________________________________113____120__ 

           ____129_________________________________________________________________________________________________________________ 
 1tw2(A) : PDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLP 
         :                                                                                                                          
 1tw2(B) : PDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLP 
           ____129_________________________________________________________________________________________________________________ 

           ______________________________________283_______________________309____316____________________________________           
 1tw2(A) : RKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPA*           
         :                                                                                                                          
 1tw2(B) : RKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPAA           
           ______________________________________283_______________________309____316____________________________________           

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		8.7
Translation
(A) 		-0.2
Closure
(%) 		95.0
Bending Residues
( green ) 		  113 - 116
  120 - 122
  129 - 130
  283 - 291
  309 - 312
  316 - 317
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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