Akap9-Braf Fusion Protein

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Akap9-Braf Fusion Protein
  Conformer 1
(PDB)
3og7 (A)
  Conformer 2
(PDB)
3og7 (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 218 0.9   451 - 484   504 - 519   526 - 718
2 25 1.49   485 - 503   520 - 525

Sequence


           _________________________________484________________503_____________519___525___________________________________________ 
 3og7(A) : DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTAPQLAIVTQWCEGSSLYHHLHAS---fEMKKLIDIARQTARGMDYLH 
         :                                                                                                                          
 3og7(B) : DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTAPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLH 
           _________________________________484________________503_____________519___525___________________________________________ 

           ________________________________________________________________________________________________________________________ 
 3og7(A) : AKSIIHRDLKSNNIFLHEDNTVKIGDFG----gSILWMAPEVIRnPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPS 
         :                                                                                                                          
 3og7(B) : AKSIIHRDLKSNNIFLHEDNTVKIGDFGLATEgSILWMAPEVIRnPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPS 
           ________________________________________________________________________________________________________________________ 

           ______________                                                                                                           
 3og7(A) : FPRILAEIEELARE                                                                                                           
         :                                                                                                                          
 3og7(B) : FPRILAEIEELARE                                                                                                           
           ______________                                                                                                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
30.4
Translation
(A)
-0.8
Closure
(%)
67.5
Bending Residues
( green )
  484 - 487
  503 - 506
  519 - 520
  525 - 526
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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