Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		3gql (C)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 165 0.92   540 - 545   564 - 639   646 - 757
2 98 1.07   466 - 539   546 - 563   640 - 645

Sequence


           __________________________________________________________________________539___545_______________563___________________ 
 3gqi(A) : *ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 
         :                                                                                                                          
 3gql(C) : YELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPP--- 
           __________________________________________________________________________539___545_______________563___________________ 

           ______________________________________________________639_______________________________________________________________ 
 3gqi(A) : FSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV 
         :                                                                                                                          
 3gql(C) : ----------eQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--------------pVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV 
           ______________________________________________________639_______________________________________________________________ 

           _________________________________________________________________                                                        
 3gqi(A) : PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                        
         :                                                                                                                          
 3gql(C) : PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEY***                                                        
           _________________________________________________________________                                                        

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		18.0
Translation
(A) 		-0.9
Closure
(%) 		82.1
Bending Residues
( green ) 		  539 - 540
  545 - 546
  563 - 564
  639 - 665
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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