Ketohexokinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Ketohexokinase
  Conformer 1
(PDB) 		6p2d (A)
  Conformer 2
(PDB) 		2hlz (C)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 262 0.72   5 - 18   34 - 101   114 - 296
2 27 0.69   19 - 33   102 - 113

Sequence


           ____________________18_____________33_________________________________________________________________101________112____ 
 6p2d(A) : ******EKQILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAPGHVADFLVADFRQRGVDVSQVTWQSQGDTPCSCCIVNNSNGSRTIILYDTN 
         :                                                                                                                          
 2hlz(C) : SGLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTILSLLGAPCAF-gS-aPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRS 
           ____________________18_____________33_________________________________________________________________101________112____ 

           ________________________________________________________________________________________________________________________ 
 6p2d(A) : LPDVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEEHNAKQPLPQKVRVSVEIEKPREELFQLFSYGEVVFVSKDVAKHLGFQSAVEALRGLYSRVKKGATLVCAWAEEGADALGPD 
         :                                                                                                                          
 2hlz(C) : LPDVSATDFEKVDLTQFKWIHIEGRNASEQVK-lQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPD 
           ________________________________________________________________________________________________________________________ 

           ______________________________________________________________                                                           
 6p2d(A) : GQLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSKGNSMQEALRFGCQVAGKKCGLQGFDGIV                                                           
         :                                                                                                                          
 2hlz(C) : GKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV                                                           
           ______________________________________________________________                                                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		14.2
Translation
(A) 		-0.1
Closure
(%) 		71.8
Bending Residues
( green ) 		  18 - 19
  33 - 34
  101 - 102
  112 - 119
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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